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Dr. Hall’s Notes

Topic

Cardiometabolic

4 pieces in this topic.

Cholesterol and Lipids on a GLP-1

Cardiometabolic

Cholesterol and Lipids on a GLP-1

Triglycerides fall a long way, HDL rises a little, and LDL barely moves — which surprises people who assumed losing weight fixes cholesterol. Here is what changes, what does not, and why your statin stays.

Feb 20264 min
Blood Pressure on a GLP-1

Cardiometabolic

Blood Pressure on a GLP-1

Your blood pressure falls as your weight does, which is a benefit right up until the point where the dose set at your old weight becomes too much. Nobody schedules the review, and the symptom of missing it is a fall.

Dec 20254 min
The Heart Data Nobody Brings Up at Dinner

Cardiometabolic

The Heart Data Nobody Brings Up at Dinner

SELECT was the trial that changed what these drugs are. A 20% reduction in major cardiovascular events, in people without diabetes — and a quiet argument about whether the benefit is really about weight at all.

Dec 20255 min
GLP-1s and Heart Failure

Cardiometabolic

GLP-1s and Heart Failure

For years the advice to a breathless patient with a preserved ejection fraction was diuretics and a shrug. Two randomised trials have changed that, and the population they studied is a large share of the people reading this.

Nov 20254 min