Topic
11 pieces in this topic.
Safety
The benefits are real and so is a risk that gets almost no attention: an older adult who loses 15% of their weight without a protein and training plan can arrive lighter, healthier on paper, and unable to get off the floor.
Safety
The contraindications are short, specific, and frequently skipped by a ten-minute online intake. The cautions are longer and more interesting. A screening guide written the way I would run it in clinic.
Safety
A stomach that empties slowly can still hold food after a standard overnight fast, which is a problem under anaesthesia. The guidance has moved on from 'stop the drug' — but the instruction to you has not changed at all.
Safety
Semaglutide is licensed from age twelve, the trial result was larger than in adults, and almost every conversation I have with parents about it is really a conversation about something else.
Safety
Every one of these drugs delays gastric emptying — that is the mechanism, not a malfunction. The question worth answering is where the line sits between the intended effect and a condition you would not want.
Safety
These drugs almost never cause a low on their own. Add insulin or a sulfonylurea and a much smaller plate, and they do — and the symptoms look enough like a dozen other things that people treat the wrong problem.
Safety
A stomach that empties slowly changes how every pill you swallow is absorbed. Most of the time that does not matter. Here is the list of times it does — starting with the one on the tirzepatide label that almost nobody has read.
Safety
Two things are true and they point in opposite directions: obesity is a well-established cause of at least thirteen cancers, and these drugs carry a warning derived from tumours in rats. Here is how to hold both.
Safety
Every one of these drugs carries a boxed warning about thyroid tumours, and it comes from rats. Whether it means anything for humans is a genuinely open question — here is what is known, what is not, and what to do with that.
Safety
Rapid weight loss makes gallstones. That was true long before these drugs existed, and it is the mechanism behind most of the gallbladder trouble people blame on the medication itself.
Safety
It appears in the warnings for every drug in this class and as a red flag on every page of this site. Here is what the evidence actually shows, and the one pattern of pain that should never wait until morning.